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Seed Probiotics review: Can this shelf-stable probiotic subscription improve gut function?

Seed Probiotics arrive in a reusable glass container with a glass travel vial.

Taking probiotics can be a reliable way to manage certain gastrointestinal issues. Unfortunately, not all probiotics are created equal — so results can be hit or miss.

Seed Probiotics, however, claim that their shelf-stable probiotic offers one of the most effective formulas and delivery systems on the market.

The brand says their probiotics are formulated to improve gastrointestinal health by improving gut barrier integrity and gut immune function, and the prebiotic outer capsule is meant to survive the digestive tract to deliver the intact inner probiotic capsule directly to your gut.

We wanted to see how Seed Probiotics stack up to other brands and test their impact on gut and gastrointestinal health, so we decided to put them to the test. Here’s what we found.

How we tested Seed Probiotics

We tested Seed Probiotics among a number of health-conscious individuals with a variety of gastrointestinal issues. This included people with mild gut issues, such as bloating and occasional upset stomach, as well as those experiencing more serious conditions like irritable bowel syndrome.

All of us had tried more than one type of daily probiotic. Many of us reported common side effects when using many other probiotics, such as stomach pain and bloating, or found that some probiotics caused no noticeable effects or improvements.

With Seed Probiotics, we were looking for an effective non-prescription solution that reduces our gastrointestinal symptoms without causing any new side effects.

What’s in Seed Probiotics?

Seed Probiotics use a proprietary 2-in-1 capsule design that houses the probiotic formula in a prebiotic casing meant to make it more resistant to stomach acid, digestive enzymes, and bile salts — and ultimately a more effective vehicle to deliver the probiotics where they need to go.

The company claims the capsules include clinically-studied probiotic strains that aren’t found in yogurt, supplements, or fermented foods.

By taking a microbe-system approach, this probiotic is designed to offer benefits to the cardiovascular system, metabolism, and skin in addition to gastrointestinal health. The formula is also purportedly the first to include bacteria strains that synthesize folate (needed to produce red and white blood cells) and increase folate production in the body as well.

This probiotic is vegan and free of gluten, dairy, and preservatives. It’s also free of 14 classes of allergens defined by the European Food and Safety Authority (EFSA).

Seed Probiotics cost

Seed Probiotics cost $49.99 per month, which falls in the middle of the price range for a month’s supply of probiotics. The Welcome Kit includes a 30-day supply of two daily capsules, a reusable glass pill jar, and a seven-day travel vial. Every month after that delivers a compostable packet with a 30-day supply of pills, which you can keep in the reusable glass jar.

The subscription is placed on automatic renewal upon enrollment; however, we found it was easy to skip or cancel any time. The price includes free shipping to the US and flat-rate shipping for international orders.

Ordering Seed Probiotics

We found that ordering Seed Probiotics was super simple. There’s only one probiotic option available, which means you won’t have to sift through different varieties or formulas. We appreciated this simplicity.

Putting in the order took very little time. All we had to do was input our credit card info and shipping address. However, we were somewhat perplexed by the user experience of the website. While it has a refreshing, new-age aesthetic, it hindered navigation for first-time site visitors. We received our Welcome Kit within a few business days of ordering.

First 48 hours taking Seed Probiotics

We followed the directions from Seed and began by taking only one capsule for the first three days. This is recommended to help your body adjust to a new probiotic. Once the three days were over, we were advised to double up going forward.

Seed cautions that new users may experience stomach pain in the first few days of use, but we actually noticed a reduction in stomach pain within the first 48 hours of taking Seed Probiotics. However, those who have never taken a similar probiotic might have the opposite experience, but this is a totally normal adjustment period that should end within a few days.

One-month results taking Seed Probiotics

After a month of using Seed Probiotics, we experienced a significant decrease in stomach bloating and stomach pain. Rather than experiencing the daily bloating we were used to, we only felt bloated after long or intense bouts of physical activity, larger meals, or meals with lots of dairy or sugar — our usual triggers. This marked a significant improvement in overall wellbeing.

Those of us with irritable bowel syndrome didn’t experience any major flare-ups, either — also a dramatic improvement. We went from frequent (once weekly or more) major flare-ups to a couple minor flares per month. Others with mild gut health concerns felt their GI tracts were functioning optimally, and overall, they felt better than before.

Overall digestive health after long-term use of Seed Probiotics

Seed was the first probiotic pill that we could take right after waking up and before eating without developing a stomachache.

Many of us experienced a long-term decrease in stomach pain and bloating, especially when taking Seed Probiotics in accordance with a balanced, mostly plant-based diet. Not only did Seed Probiotics cut down on bloating and pain, they also helped keep symptoms at bay while we were sedentary, stressed, or sleeping less.

We were also impressed that Seed Probiotics alleviated the typical upset that comes with prescribed antibiotics. Past experience with other probiotics taken in tandem with a prescribed antibiotic has resulted in negative digestive symptoms.

Some of us experienced benefits secondary to improved digestive health, such as a reduction in mild to moderate acne. Our complexions improved, plus breakouts healed noticeably faster.

Shelf-stability of Seed Probiotics

Seed Probiotics are touted as shelf-stable, and based on our experience, we’re inclined to agree. This was an added convenience compared to other probiotics with a high strain count that tend to require refrigeration.

After leaving the bottles on our bedside tables for over a month, we didn’t notice a decrease in potency. This was especially appealing to travelers in our group. The glass travel vial is durable and shatter-resistant. We were able to carry the vial in our carry-ons for flights without any damage or breakage, which impressed us.

Seed Probiotics packaging

We felt that one appealing attribute of Seed Probiotics is their sustainability initiative. All shipping and packaging materials are either reusable or compostable.

The first delivery of Seed Probiotics comes with a glass pill bottle and a glass travel vial, both of which have reusable plastic lids. These containers are packaged in biodegradable paper foam and a biodegradable algae paper box. After the first month, users receive their probiotic pills in a compostable bag that can be emptied into the glass pill bottle and then composted.

Seed Probiotics pros

Overall, we were impressed with Seed’s impact on our gut health. We experienced positive results in as soon as 48 hours, and sustained benefits to digestion and skin health within a month.

We felt Seed Probiotics delivers on its claim as being a high-potency formula. Given the improved digestive function and overall feelings of wellness we experienced, we agree that Seed Probiotics can significantly improve several health and wellness concerns.

Seed’s sustainability initiatives are also incredibly appealing, and in our opinion, this helps offset the formula’s slightly higher cost compared to some over-the-counter probiotics (which, in the end, didn’t even work for us).

Seed Probiotics cons

Seed Probiotics can have moderate side effects, most noticeably in our testing with an increase in burping; however, it wasn’t a deal-breaker when combined with the overall benefits we experienced.

Are Seed Probiotics worth it?

Seed offers a well-formulated probiotic that delivers short- and long-term results to a wide variety of users, including health-conscious individuals as well as people managing issues like irritable bowel syndrome. Because we experienced fewer side effects and more positive benefits than other over-the-counter probiotics, Seed makes a great option for those seeking a non-prescription way to improve gut health as well as overall wellbeing.

If you believe you would benefit from Seed Probiotics, we recommend talking with your doctor first, especially if you’re currently undergoing treatment or managing other health conditions.

Sian Babish is a writer for BestReviews. BestReviews is a product review company with a singular mission: to help simplify your purchasing decisions and save you time and money.

BestReviews spends thousands of hours researching, analyzing and testing products to recommend the best picks for most consumers. BestReviews and its newspaper partners may earn a commission if you purchase a product through one of our links.

Distributed by Tribune Content Agency, LLC.

Taking probiotics can be a reliable way to manage certain gastrointestinal issues. Unfortunately, not all probiotics are created equal— so results can be hit or miss. Seed Probiotics, however, claim that their shelf-stable probiotic offers one of the most effective formulas and delivery systems on the market.

I Took Seed’s Probiotics For One Month – Here’s How My Gut Health Changed

Seed daily synbiotic review

Health and Wellness products are in constant supply in our office, so when one of us has rave reviews we all take note. Enter Seed’s Daily Synbiotic, a probiotic and prebiotic backed by both science and impressive individualized support via a day-by-day game plan for optimal digestive health. Our teammate, Alyssa Mandel, gave them a try for 30 days—here was her experience…

Here’s the truth: No matter how clean I eat, how much I workout, or how consciously I hydrate and supplement, my belly can still get a little bulge. I’ve spent years trying to ease the physical (and emotional) discomfort of occasional bloating. Despite my abundance of resources as a wellness editor, I have never been able to find a solution that sticks.

After two days of taking Seed’s Daily Synbiotic, my skinny jeans seemed to fit better than ever. By week three of daily use, my unsolvable bloat problem was apparently gone.

Seed is a brand that’s gained well-earned buzz for its focus on science and sustainability. Their star product, the Daily Synbiotic, is a probiotic plus prebiotic developed by an impressive roster of scientists, doctors, innovators and entrepreneurs. It’s formulated for optimal digestive health, and has deep data to back up its innovative design.

Curious about the hype, and determined to get my gut health in check, I committed to taking the Daily Synbiotic every night for a month. In true Capricorn fashion, I kept my lifestyle rigidly consistent and tracked my experience with meticulous detail.

The results were impressive—and obvious. While I’ve taken probiotics in pretty much every form, I’ve never experienced such observable improvements, and definitely not this fast. Over the course of a month, I didn’t experience bloat, constipation or loose stools…not once. My skin became more smooth and clear (dare I say, glowing?), and I felt dramatic shifts in my energy and mood.

The Problem In Our Gut

Here’s a fun fact: you are only half human. The other 50% of your body is microbial—meaning, t here is one microbial cell for every one of your human cells. and fifty percent of your body is microbial cells. That means tending to the tiny universe of microbes (38 trillion of them, to be specific) that lives in our bodies is key to maintaining overall health.

The ecosystem in our gut has an especially strong influence over our entire system, from gut immune and metabolic function to cardiovascular, skin and reproductive health. Probiotics are one way to aid our gut flora, but with so many options on the market and so little regulation in the industry, it can be challenging to find a reliable supplement.

According to Seed’s founder, Ara Katz, “Many of the products out there that claim to be probiotic, like some kombuchas or probiotic nuts, for example, don’t actually qualify as one. Just because something contains live microorganisms, doesn’t mean it satisfies the scientific definition of a probiotic—’live microorganisms that, when administered in adequate amounts, confer a health benefit on the host,’ a definition authored by the United Nations World Health Organization Expert Panel chaired by our Chief Scientist, Dr. Gregor Reid, in 2002.”

In response, Seed strives to bring much needed precision, education and efficacy to the probiotics category.

seed probiotics

I Tried Seed’s Daily Synbiotic…Here’s What Happened

While I felt supported from day one, it’s not simply because I’m a wellness editor writing this piece. Before my subscription arrived, I already found several emails in my inbox from the Seed team. They offered a digestible dose of science and a day-by-day game plan for starting my new probiotic protocol. This is an experience every customer gets.

Finally, my green box showed up. Seed’s packaging caught my eye right away: The refillable glass jar is elegant AF, and came nestled in an ultra-sustainable mycelium tray grown from mushrooms. (Yes, mushrooms.) The first shipment also contained a small glass vial for travel that holds up to a week of capsules. Subsequent shipments will contain 30-day low-waste refills for the glass jar (in biodegradable packaging, of course).

I started incorporating the emerald green capsules into my nightly routine, taking them down with a full glass of water two hours after dinner. My body adjusted quickly and smoothly. After just a few days, I noticed I was already waking up without bloating or any other digestive issues.

After a week, I wrote this in my journal: I’ve been taking Seed every night and my stomach looks flat, I feel refreshed and amazing, regardless of what I’ve eaten the night before. My gut feels calm and my digestion is more regular than ever.

The benefits became more and more obvious over the course of a month. Without changing any other habits, I noticed that my skin had a new ‘alive’ look to it, and I woke up so energized that my black tea addiction became obsolete. I even noticed a significant uptick in my mood and stress tolerance.

The Science Behind Seed’s Daily Synbiotic

According to Seed, the Daily Synbiotic is “the first probiotic to take a ‘microbe-systems approach’ with clinically-studied, strain-specific benefits beyond digestive health, including cardiovascular health, dermatological health, gut immune function, gut barrier integrity and micronutrient synthesis .”

Each d ose (two small but mighty capsules) combines 24 clinically-studied, naturally-occurring probiotics strains that are not found in yogurt, most supplements or fermented foods.

While other probiotics incorporate strains from animal or soil, Seed only selects strains that are naturally occurring in the human body. The benefits are validated by 17+ strain-specific clinical studies and Seed’s own clinical research.

Most impressive is the way Seed keeps the probiotic strains alive and active. Bacteria are sensitive to light, temperature, and moisture, meaning most hardly survive the trip from manufacturer to store shelf, much less your digestive process. Seed puts its probiotics inside a vegan capsule and inside another prebiotic outer capsule, 2-in-1 nested capsule technology to ensure that bacteria stay alive and viable to your colon, where their work begins. Because of this, the Daily Synbiotic is shelf stable for 18 months and requires no refrigeration.

The Final Verdict

I was skeptical but hopeful when I started—and completely blown away by the end of my one-month trial. Seed is setting a gold standard for probiotics and completely revolutionizing modern gut health as we know it. Would I do it again? I’m already counting the days until my next shipment arrives.

To try Seed’s Daily Synbiotic for yourself, click here and use code: CHALKBOARD for 20% off your first shipment.
This story is brought to you in partnership with Seed.

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We tried Seed's Daily Synbiotic, and here's what happened. (Hint: never felt better.)