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pumpkin seeds and cholesterol

Supplementation with pumpkin seed oil improves plasma lipid profile and cardiovascular outcomes of female non-ovariectomized and ovariectomized Sprague-Dawley rats

Affiliation

  • 1 Department of Basic Medical Sciences, Pharmacology Section, University of the West Indies, Mona Campus, Kingston 7, Jamaica, West Indies. [email protected]
  • PMID: 18567058
  • DOI: 10.1002/ptr.2381

Supplementation with pumpkin seed oil improves plasma lipid profile and cardiovascular outcomes of female non-ovariectomized and ovariectomized Sprague-Dawley rats

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Authors

Affiliation

  • 1 Department of Basic Medical Sciences, Pharmacology Section, University of the West Indies, Mona Campus, Kingston 7, Jamaica, West Indies. [email protected]
  • PMID: 18567058
  • DOI: 10.1002/ptr.2381

Abstract

Pumpkin (Cucurbita species) seed oil (PSO) is a rich source of phytoestrogens and the aim of this study was to examine the effect of PSO supplementation on the total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), triglycerides, high density lipoprotein cholesterol (HDL-C), systolic and diastolic blood pressure in non-ovariectomized and ovariectomized Sprague-Dawley rats. Female rats weighing 220-300 g were divided into non-ovariectomized rats for supplementation with corn oil (control CO; n = 6) or PSO (control PSO; n = 5) and ovariectomized rats for supplementation with corn oil (OVX/CO; n = 6) or PSO (OVX/PSO; n = 5) for 5 days per week for 12 weeks (corn oil 40 mg/kg or PSO 40 mg/kg given orally). Systolic and diastolic blood pressures were measured weekly. Blood was collected at the end of the period for plasma lipid assays. Control PSO had lower TC, LDL-C, triglycerides and higher HDL-C than the control CO. The OVX/CO had higher TC, LDL-C, triglycerides and lower HDL-C than the control CO and these changes were prevented in the OVX/PSO rats. PSO supplementation also resulted in lower systolic and diastolic blood pressures in both non-ovariectomized and ovariectomized rats. It is concluded that PSO supplementation can prevent changes in plasma lipids and blood pressure associated with inadequate oestrogen availability.

Pumpkin (Cucurbita species) seed oil (PSO) is a rich source of phytoestrogens and the aim of this study was to examine the effect of PSO supplementation on the total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), triglycerides, high density lipoprotein cholesterol (HDL-C), systolic a …

Lower cholesterol with pumpkin seeds

Lower cholesterol with pumpkin seeds

Halloween and the orange pumpkin go together. But today we look at how the smallest part of the pumpkin, the seed has a lot of health benefits; rather than just being a good ‘time pass’ while watching your favourite drama show.

Pumpkin as a vegetable is low in cholesterol; hence it is beneficial for your weight loss diet. But let’s eat to the centre of the pumpkin and find out more health benefits of pumpkin seeds.

Pumpkin seeds reduce the chance of prostrate cancer. Pumpkin seeds can reduce the progression of benign prostatic hypertrophy (this can lead to cancer) and ease prostrate cancer.
Pumpkin seeds have the ability to protect you from osteoporosis and arthritis. This seed is rich in zinc, whereas osteoporosis is the outcome of low zinc levels.

The chemical component of phytosterols present in pumpkin seeds has the ability to suck out cholesterol from the body. It also puts a plug on cholesterol absorption in the body.

Most of us know that berries are a good source for anti-oxidants, and now you can add pumpkin seeds to the list too. Stop inflammation with pumpkin seeds.

For vegetarians, add pumpkin seeds to your list of foods rich in protein.100gms of seeds on a daily basis provide 54 percent of the daily requirement in terms of protein.

Most of us pop pills to replenish deficiency of vitamin B-complex, try pumpkin seeds next time. Pumpkin seeds are a good source for vitamin B like thiamin, riboflavin, niacin, pantothenic acid, vitamin B-6 and folates.

For those who are down in the dumps, pumpkin seeds can help fight through depression. The chemical component L-tryptophan is the secret ingredient to boost your mood.

Did you know that pumpkin seeds can prevent kidney stones? Studies suggest that pumpkin seeds can help prevent certain kidney stone formations like calcium oxalate kidney stone.

Apparently pumpkin seeds also hold the secret to fighting parasites, especially tapeworms.

Pumpkin seeds can also be a good foundation for a beauty treatment. It keeps your skin healthy, glowing and vibrant.

Halloween and the orange pumpkin go together. But today we look at how the smallest part of the pumpkin, the seed has a lot of health benefits…