Best CBD Vape Juice 2022 – Tasty Classics For Pain & Anxiety Relief With the world of CBD products growing with each new piece of research to support the use of this cannabinoid, it should come At VAAY, we’re more than impressed at how far CBD, also known as cannabidiol, has come- from starting out as a niche part of subculture to becoming a huge part of the health and wellness community. We’re even more impressed at the variety of different ways one can take CBD. From oils to topicals and vape pens, CBD is a
Best CBD Vape Juice 2022 – Tasty Classics For Pain & Anxiety Relief
With the world of CBD products growing with each new piece of research to support the use of this cannabinoid, it should come as no surprise that the number of CBD providers has also increased. And with people trying to take advantage of CBD products while they’re on the go has come a growing desire for CBD vape juice.
We know that it can be challenging to find the ideal CBD vaping oil products, that’s why we have identified the top five CBD vape oil providers. In addition, we have listed the advantages and disadvantages of each brand, leaving our readers with little to do but read and click.
Top 4 CBD Vape Juice Brands
– Editor’s Choice – Best CBD Vape Juice – Runner Up – Honorable Mention – Worthy Mention
1. CBDfx – Editor’s Choice
- Numerous discount opportunities
- Multiple unique flavor options
- Extensive satisfaction guarantee
- Highly-rated products
- Verified potency
Why Shop With CBDfx?
People who shop with CBDfx are assured that the CBD vape oil they receive is created from organic hemp grown in the United States. CBDfx also boasts that their vaping CBD products contain a perfect 50:50 ratio between vegetable glycerin and propylene glycol. Available in terrific flavors such as Strawberry Kiwi, Blue Raspberry, Strawberry Milk, Wild Watermelon, and Fresh Mint, CBDfx boasts that all its products are created under cruelty-free conditions. The company also assures that its CBD vape juice products are solvent-free. For ease of worries, CBDfx offers accessible lab reports on the product pages of its CBD isolate vape juice options.
Another advantage gained when shopping with CBDfx is the surety that all vape products on offer are created from human-grade ingredients. CBDfx even goes as far as to guarantee the potency of its vape products. With accreditation from the Hemp Industries Association and National Hemp Association, CBDfx provides quality CBD vaping products. The company offers a 60-day satisfaction guarantee, allowing a full refund in the unlikely case that someone is not completely satisfied with their experience.
What Do Customers Think Of CBDfx?
CBDfx has amassed one of the largest ranges of positive product reviews across its CBD vape juice products. The company boasts more than 1000 reviews with a range of ratings from 4.8 to 4.9-stars. In fact, the company’s Blue Raspberry has gained more than 700 reviews with an average rating of 4.9-stars. Buyers have noted that the product boasts excellent taste and a pleasant smell. Customers have also praised the delivery time and the overall potency of the product. Further reviews have indicated the product’s effectiveness when treating pain and allowing for a transfer away from harmful nicotine products.
Are CBDfx’s Vape Products Worth The Price?
CBDfx offers sitewide discounts when using the company’s widely advertised discount codes. Customers can save up to 25% off their overall order as long as they are purchasing three or more items. It’s also possible to split purchase price into four manageable portions using the Sezzle payment plan available on the site. Further discounts can be earned through the company’s loyalty program, where 100 points can be redeemed for $5. Currently, CBDfx offers three main strength options for vaping CBD juice:
- 500mg CBD
- 1000mg CBD
- 2000mg CBD
Our selection of CBDfx as our Editor’s Choice and the best CBD vape juice provider on our list comes from a combination of accredited manufacturing processes, organic ingredients, and potency. These factors, along with affordable products and numerous discount opportunities, have set the company ahead of others in the CBD oil industry.
2. Secret Nature – Runner Up
- Affordable prices
- Full-spectrum options
- Discount opportunities available
- Discrete packaging
- No CBD isolate options
Why Shop With Secret Nature?
Secret Nature boasts that its full-spectrum CBD vape juice products contain essential cannabinoids and terpenes, including CBN, THC, CBG, and CBC. The company also assures that its CBD e-liquid only contains minute traces of THC to balance the 55.3% CBD that is in its formula. In addition, Secret Nature’s vapor cartridges are created from live resin and terpenes extracted from fresh cannabis flowers frozen upon reaping. Secret Nature accredits this practice for the potent flavors and benefits customers can reap from their CBD vape products. The company also boasts that its products contain no plastics, are non-GMO and vegan-friendly. Lab reports of all the company’s products are accessible on the Laboratory Tests Results page.
Secret Nature uses no artificial flavors to disguise the taste or stretch the quantity of their CBD e-liquid products. In fact, the company boasts that its ingredients are 100% organic and that the cannabis flowers used in their production are grown indoor and lab tested before use. While the company doesn’t offer broad-spectrum or CBD isolate options, its products are discreetly packaged and available in the flavors Forbidden Fruit, Grape Ape, Lemon Diesel, and Orange Royale. Customers can also purchase vape cartridge batteries and chargers, along with disposable vapes from Secret Nature, creating a one-stop shop for CBD vaping fans.
What Do Customers Think of Secret Nature?
Secret Nature has amassed numerous positive ratings ranging from 4.5 to 5-stars. The company’s more popular products, such as the delta-8 THC vape pen cartridge, boast more than 400 reviews with a 5-star average. Buyers have indicated that using the vape allows for relaxation and calm. Clients have also noted quick responses by the company’s customer service team and a noticeable reduction in pain as reasons why they would seek to continue shopping with Secret Nature.
Are Secret Nature’s Vape Products Worth The Price?
Secret Nature provides more than ten CBD vaping options to choose from, an offer that includes the opportunity to receive two free pre-rolls on purchases over $100. In addition, if you are looking for further discounts, you can sign up for the company’s subscription program saving yourself 15% off your orders with a delivery every 30 days. Secret Nature currently offers four buying options:
- 700mg Cartridge
- 700mg + Battery & Charger
- 1200mg Cartridge
- 1200mg + Battery & Charger
Through a combination of organic ingredients, affordable pricing, and a wide array of vaping supplies, Secret Nature has created a place for itself in the CBD vape juice industry. These factors combined with its discreet packaging, potent products, and very satisfied customer base have more than earned the company its enviable spot on our best CBD vape juice list.
3. Extract Labs – Honorable Mention
- Brilliant loyalty program
- Affordable products
- International shipping
- Unique flavor options
- Only full-spectrum options available
Why Shop With Extract Labs?
Extract Labs’ CBD vape juice is created from a high-quality formula of CBD, CBT, and CDBG. The CBD and other cannabinoids are CO2 extracted, and its extract tanks contain no fillers. Available in the flavors Clementine, Martian Candy, Ogre Berry, Guava Jam, and Sour Ghost, Extract Labs’ full-spectrum CBD e-liquid contains no traces of the harmful vitamin E acetate. The company also boasts one of the only international shipping opportunities on the CBD vape market.
Extract Labs’ potent CBD e-liquid products have 500 mg of cannabinoids per cartridge, ensuring that the products are some of the most effective on the market. Another advantage to be found in the purchasing of Extract Labs’ CBD vaping products is the company’s promise that all the hemp used in its manufacturing process is American grown. In fact, Extract Labs ingredients and manufacturing process have gained the company numerous awards, including the Indo Expo Best Extractor Reward of 2019 and the CBD Examine Authenticity Award. Anyone who is still unconvinced by the company’s accreditations can view the third-party lab test results of all Extract Labs CBD vape juice products on the company’s Lab Reports Batch Database and each product page.
What Do Customers Think of Extract Labs?
Extract Labs has gained consistent positive reviews across the ten CBD vape products that the company offers, with a 5-star average dominating the vast majority of products. The company’s most popular flavor, Sour Ghost, has achieved almost 100 reviews with an average of 5-stars. The product has been praised for the boost of energy that it provides. Clients have also noted that the product is particularly effective in treating anxiety.
Are Extract Labs’ Products Worth The Price?
Extract Labs offers one of the most extensive discount programs in the CBD industry. Up to 50% can be saved off an order if they qualify for a discount. Currently, the company offers discount opportunities to:
- Veterans and active military
- First responders
- Health care workers
In addition, international customers, those on disability or with low income, can also apply for these discounts. Extract Labs requires only identification and proof of profession, income, or disability allowance to start the decision process. Extract Labs only offers one 500 mg version of their extract tank that is available for only $29.00
Extract Labs has more than earned a place on our list with its extensive discount opportunities, affordable, potent products, and opportunities for international buyers. Combined with its unique flavors and easy-to-use website, Extract Labs is a vape CBD provider to take note of.
4. Just CBD – Worthy Mention
- 15-day full refund policy
- Numerous flavor options
- Affordable products
- High customer ratings
- Website is a bit bare
Why Shop With JustCBD?
Established in 2017, JustCBD obtains its organic hemp from Oregon farms in the United States. In addition, the company claims that its products contain no synthetics or THC. JustCBD assures that their CBD products result from careful research and that the company will not skimp on quality just to improve the quantity of their products. For further assurance, the company lists all the ingredients included in its CBD vape oils, allowing customers to decide if the product is the one for them. Additionally, JustCBD provides lab reports for all its products.
JustCBD currently offers over five delicious CBD juice options, including Strawberry Cheesecake, Cookies, Blue Dream, and Pina Colada Ice. JustCBD is a member of the Florida Hemp Council, meaning that the company is held to a high testing standard and must continue research into CBD improvement as part of the council. While the website might seem a bit bare, JustCBD operates with its clients’ needs at the forefront of its operation, and as such, the company is more than willing to arrange full refunds for any unopened item within 15 days of purchase. The company also promises that in the unlikely case that order cancellation is needed, this can be quickly arranged by phone or email.
What Do Customers Think Of JustCBD?
JustCBD boasts a host of positive reviews for its CBD vape juice. The company has amassed an average of 4.8-stars across its numerous size ranges, with the most popular Pineapple Express gaining more than 100 reviews across its size range. Buyers have praised the product’s natural taste, comparing it favorably as opposed to other vapes of similar flavor that apparently have an artificial tinge to their taste. Customers have also noted that the products effectively treated anxiety symptoms.
Are JustCBD’s Products Worth The Price?
Anyone shopping with JustCBD can take advantage of the company’s free shipping offer on any order over $50. In addition, the company offers an Autoship & Save option that can save 30% of the price of their favorite product. This offer can reduce the company’s already cheap 100 mg CBD vape oil from $12.00 to $8.40 per purchase. In addition to this price, JustCBD also offers the choices of:
- 250mg Vape
- 500mg Vape
- 1000mg Vape
- 1500mg Vape
JustCBD presents a comprehensive, affordable range of high-quality CBD vaping products. When combined with the company’s approach to research and manufacturing, this factor has more than cemented JustCBD’s place on our list..
Criteria Used To Choose These CBD Vape Juice Brands
We have designed our list to ensure that the process of finding the best CBD vape juice provider for you is as painless as possible. Thus, we have highlighted the factors that people find most important on their CBD vape oil journey. We have included these factors in each of our reviews, presenting our readers with an unbiased profile of each CBD e-liquid provider. The three factors we have included are:
- Company Aim And Reputation – We want our readers to be introduced to only the best CBD vape juices possible. To achieve this, we have carefully scrutinized the background and aim of each company on our list. We have only recommended providers who put customer needs at the helm of their business. We filter out any potentially scammy CBD companies and only offer up those with the best reputations.
- Customer Reviews – To ensure that the CBD e-liquid brands that we have included on our list provide the most efficient and potent vaping CBD oil products possible, we have turned to past customer experience. We have provided average star ratings so readers can quickly scan the information. We have also included statements or complaints that we found particularly persuasive.
- Cost – Potential scammers and companies looking to cut corners by imitating legitimate CBD providers can easily con you out of hundreds of dollars. To combat these fraudulent attempts, we have ensured that the companies on our list match price with quality. In addition, we have checked the prices and made sure that they match what is expected of CBD e-liquid products.
What Is CBD Vape Juice?
CBD vape juice is a form of vape oil or e-liquid that replaces the more commonly used nicotine with the compound CBD. Also known as CBD vape oil and CBD e-liquid, CBD vape juice boasts many benefits due to its main component CBD, much like its counterpart CBD oil.
However, despite one of its names, CBD vape oil is not an oil, and it is strongly advised that people should not try to use CBD oil as an alternative to CBD vape juice. In fact, one of the few things the two products share is the presence of CBD. CBD, which is the short term for the compound cannabidiol, is found in the cannabis and hemp plants.
CBD vape juice is specially formulated with several key ingredients that make the product suitable for vape pens. Formulas usually contain vegetable glycerin (VG), propylene glycol (PG), the flavor of choice, and any other unique additive that a CBD vape juice provider might choose.
Vegetable glycerin is used in e-liquid to thicken the product, producing the dense clouds users experience during vaping. Vegetable glycerin is often used as a food additive, is entirely safe, and has a sweet taste. On the other hand, propylene glycol creates a sensation that mimics the effects of tobacco cigarettes, thus making the transition between cigarettes and vaping pens much easier. Much like vegetable glycerin, propylene glycol is also a food additive bearing a sweet taste.
Loke CBD oil, CBD vape juice comes in full-spectrum, broad-spectrum, and CBD isolate options. And, like with CBD oil, even full-spectrum products will contain only minute trace quantities of THC, meaning that none make a user ‘high’. Available in several accessible and affordable packages, CBD vape juice provides an easy way to get a CBD dose while on the move.
How To Choose The Right CBD Vape Oil
With hundreds of CBD vape products available worldwide, finding the perfect product for yourself might seem like a daunting task. Using our handy article finding the CBD vape juice provider is easy, but we have also considered choosing the most suitable CBD vape juice for readers.
- Concentration – The strength of the CBD in the e-liquid that you purchase is important. Those who work in particular jobs that require drug testing or complete, unbroken concentration might find that full-spectrum CBD vape oils are not for them. In such cases, we would recommend either CBD isolate vape juices or broad-spectrum CBD vape juice. On the other hand, anyone looking for a quick dose to relieve pain symptoms or anxiety and stress would be better off with the heavier full-spectrum CBD e-liquid options.
- Flavor – Unlike CBD oil, CBD vape juices are almost guaranteed a wide range of flavors. Choosing the CBD e-liquid that best suits your taste buds is the easiest way to keep from straying back to more harmful habits such as tobacco cigarettes.
- Packaging Discretion – While some might enjoy bright and attention-grabbing packaging, others who are trying to be discrete about the transportation and use of their CBD vape juices might not appreciate these features. Several providers on our list and their products will be a boon for those people as the CBD vape juices are easy to use and subtle enough to avoid detection.
- Useability Time – The length of time your CBD vape juice lasts is essential when deciding on the perfect product. The length of use is significant for those who have signed up for a subscription program. Purchasing the CBD vape juice that could best accommodate your needs is made difficult by providers who haven’t accurately labeled the length of use of their products.
- Delivery Ease – One of the essential parts of the CBD e-liquid purchasing process is delivery. Whether it pertains to the cost of delivery or the time scale, finding a product that will be there when you need it is imperative.
By combining these factors and personalizing them to suit your needs, a person can easily find the perfect CBD vape juice. Now all our readers need to do is build their CBD vape oil profile and click on one of our five providers to get the best possible CBD vape juice experience.
Benefits Of CBD Vape Oil
Due to its inclusion of cannabidiol, CBD vape juice boasts the numerous benefits of CBD . Numerous studies into the effects of CBD have found that the compound can influence pain, mental health, and sleep patterns in humans and animals. These influences are amplified in CBD e-liquid due to the process of consumption. The inhalation of CBD via vape juice allows for increased bioavailability, ensuring that the CBD in the product is absorbed and circulated at an accelerated rate.
One of the most popular uses of CBD vape juice is pain management. Research such as “Selective Cannabinoids for Chronic Neuropathic Pain” by Meng et al. (2019) has found that certain cannabinoids provide pain relief for individuals suffering from chronic neuropathic pain. In addition, further research into the impact of CBD has expressed that the compound works as an anti-inflammatory agent, providing relief for patients diagnosed with arthritis and other joint pain focused ailments.
Another source of benefit for the practice of using CBD vape oil can be found in the impact of CBD on seizures. In “Cannabidiol As A Treatment For Epilepsy”, William and Robertson (2017) found that CBD proved to be a reliable treatment source for epilepsy. In addition to this, a study by Bitencourt and Takahashi (2018) found proof to support that CBD could potentially help individuals who have PTSD by assisting them in managing the disorder’s symptoms.
People suffering from anxiety and depression might also find relief using CBD vape oil. This release from the grip of these mental disorders is due to how CBD interacts with the serotonin receptors in the body. By improving the body’s natural attempt at homeostasis, CBD can potentially lessen the symptoms of anxiety and depression.
The benefits of using CBD oil and CBD vape juice extend further into the aspects of appetite management, sleep pattern control, and in some cases, the managing of the aftereffects of chemotherapy. Some buyers have even turned to CBD vape juices to kick the harmful habit of tobacco cigarette smoking. When combined with the more specific benefits of CBD vape juice, including ease of use on the go, flavor options, and faster absorption, it should come as no surprise that CBD vape oil boasts such a growing base.
How To Vape CBD E-Liquid?
You must vape correctly to get the most out of your CBD vape juice experience. First, it is essential to note that while CBD vape juice, vape oil and e-liquid are sometimes colloquially referred to as CBD oils, both products are very different. Due to the chemical makeup and consistency of CBD oil, using the products as a replacement for CBD vape juice is not advisable. Secondly, to ensure that your vaping experience allows you all the required benefits of your CBD vape oil, you must ensure that you have chosen the correct CBD vape oil products.
Another factor to be considered when vaping is your dosage. The impact of CBD in your CBD vape oils will vary depending on factors such as weight, the issue being treated, the concentration of the CBD, and metabolism. Therefore guidelines must be followed that are provided by their CBD products supplier. It is advised that new clients should always start with a low amount of 1 or 2 mg per dose. Customers who take other medications or are worried about an underlying illness should consult a medical professional before using CBD vapes.
Another critical factor to consider for your vaping experience is the quality of your equipment. Faulty vaping pens and pods can often distract from the overall experience. So, while it might be cheaper to purchase a disposable pen, you should continually monitor the quality of the item you are using.
When using a vape pen, it is advised that you allow up to ten minutes after filling your pen’s tank with CBD vape juice for the coils to saturate thoroughly. For the best experience, you should take a long draw, but one that still feels natural. A few seconds per draw is best, but shorter pulls might be better for new users. Try to keep the vapor in your lungs for several seconds before exhaling. New users should again allow time to fully experience the effect of the CBD vape on their system. Pauses of five to ten minutes are considered optimal to prevent accidental overuse. Always remember to clean your vape tank regularly.
Depending on the condition you are trying to treat, vaping once or twice a day is usually expected. However, some users, such as those with pain issues, might require additional vaping sessions. Always be careful never to use more CBD vape than is recommended by your supplier.
Is It Safe To Vape CBD E-Liquid?
When discussing the overall safety of vaping CBD juice, it is essential to compare the practice to that of vaping substances such as nicotine or regular tobacco smoking. The danger in the practice of tobacco smoking comes from the inclusion of harmful chemicals in the cigarettes themselves, which might include tar, formaldehyde, and ammonia. These chemicals are added to flavor the cigarette but actually function as carcinogens. In addition, nicotine which is included in both tobacco cigarettes and certain non-CBD vaping products has an addictive effect that many spend years trying to overcome.
Another harmful substance found in some vapes is vitamin E acetate. This compound is used as a thickening agent in some vape oil and juice Products. While not particularly dangerous in most applications, when inhaled, vitamin E acetate sticks to the lungs and is believed to lead to the formation of certain respiratory conditions.
On the other hand, the practice of vaping CBD has yet to be found to have any adverse effects. In fact, the transparency of many CBD vape providers, especially those included on our list, allows peace of mind knowing that their products are safe to use. In addition, the use of third-party testing and manufacturing process accreditation by numerous CBD governing bodies provides added pressure on the CBD industry that ensures products are high quality and bear appropriate warnings. However, pregnant and breastfeeding people are advised not to vape CBD. In addition, checking with a medical professional before starting CBD vaping is essential if you have underlying illnesses or take medication.
Finally, when the multiple advantages of using CBD, which include anxiety relief, pain management, and relaxation, are compared to the costs of regular tobacco smoking or even vaping non-CBD products, the results are clear. vaping CBD is a much safer and more beneficial practice than any alternative. And with more research into the practice emerging every day, not taking advantage of our article’s guidance and the current market would be foolish.
Can I Get High Off Of CBD Vape Juice?
It is a common misconception that vape juice and vape oil created from CBD will get a person high. However, the truth is that the cannabinoid that produces this ‘high’ is THC or tetrahydrocannabinol. While this cannabinoid is included in some CBD vaping cartridges, it is usually only present in a minute quantity of less than 0.3%, which is the threshold of regulation imposed in most states. This percentage means that the amount of THC found in the vast majority of vaping products cannot induce a high..
There is also the added security of using CBD isolate vaping products, wherein all traces of THC are entirely removed. This form of CBD product is best for anyone who requires regular drug testing as even minute traces of THC can sometimes be flagged. You can also take advantage of broad-spectrum vaping, allowing them to gain the benefits of the entourage effect while not having to worry about the presence of THC.
The world of CBD vaping has opened up a number of opportunities to enjoy the benefits of using CBD. Through a combination of affordability and accessibility, anyone can now enjoy their CBD products without the hassle often found when using CBD oils. Using our brief article, buyers now have the chance to choose the perfect supplier and CBD vaping product without extraordinary time spent researching. With only the click of a button, our readers can start their CBD vaping journey into much-needed relaxation.
Just Breathe: Can a CBD Vape Help Your Anxiety?
At VAAY, we’re more than impressed at how far CBD, also known as cannabidiol, has come- from starting out as a niche part of subculture to becoming a huge part of the health and wellness community. We’re even more impressed at the variety of different ways one can take CBD. From oils to topicals and vape pens, CBD is as versatile as it is helpful for the system in a range of ways. However, today, we’re going to narrow CBD’s benefits by focusing on one question: how valuable can a CBD vape be for soothing anxiety symptoms quickly and effectively?
Because, where there’s anxiety, there tends to be an onslaught of worry, fear, paranoia, and other unpleasant symptoms. We know that an anxiety attack can be hard to manage without a quick, efficient fix. It’s easy to let heart palpitations, nausea, and fear of failure get to you- with panic attacks often made worse with the fact that it can be hard to determine when or where an anxiety attack can hit you- so, at VAAY, we’ve found a CBD-infused supplement to get your anxiety in order whenever you feel you need it. Not only is a CBD vape perfect for transporting around, but it is also fast-acting and can be infused with a range of flavours. The perfect solution for those who want to combat their anxiety quickly.
And, as it turns out, a CBD vape is the quickest, most effective way to get CBD working in your system. There’s very little waste, very high bioavailability, and, overall, little to no fuss. With a CBD vape, you know you’re going to feel CBD’s potential therapeutic effects sooner, not later. At VAAY, we love an effective product- which is why we have a fantastic selection of vape pens for you to choose from, to intensify flavour, promote the CBD’s strength, and, above all, provide a method that prioritises more efficiency and less waste.
The Benefits of Vaping
A CBD vape can be an incredibly quick way to potentially curb any rising symptoms of anxiety. This is because, when we inhale CBD (in its vapourised form), our lungs pretty much ensure the CBD goes directly into our bloodstream with little fuss.
This differs significantly from when we ingest CBD in the form of oils, capsules, or edibles- because when we swallow anything, we’re taking it all the way into our digestive tract to be, subsequently, metabolised by the liver. This can result in slower, less intense results- and very little bioavailability.
The Importance of Bioavailability
What is bioavailability? Well, when we talk about CBD’s bioavailability, what we really mean is: how much of the CBD enters our bloodstream, in proportion to how much we took? Bioavailability could also refer to how effective a method of taking CBD is when it comes to getting the most CBD into our bloodstream, with little to no waste. To answer that question simply: a CBD vape has the highest bioavailability, when compared with even the best CBD oils. There’s more than one way to take CBD- and every single method has its pros and cons. But, if we’re concerned with getting the CBD into our system quickly and effectively, vaping is the way forward.
CBD Absorption and The ‘First-Pass Effect’
When we orally take CBD, the cannabidiol ends up in our liver, where it gets metabolised. Not only does the process of digestion usually take 1-2 hours, when CBD does enter the liver, it undergoes something known as the ‘first-pass effect’. In a nutshell, this is when the CBD is metabolised (by the liver) which then results in a lower concentration by the time it gets absorbed into the bloodstream. The CBD then takes action less intensely due to lower overall levels reaching the bloodstream post-digestion.
Another reason why CBD has a lower bioavailability when we take it orally is due to CBD being hydrophobic- meaning, CBD oil and water (in the body) don’t really mix. So, when we ingest CBD, it tends to escape the blood and accumulate in the fatty tissues of our muscles- less CBD can actually be transported by the blood to our ECS receptors, where therapeutic action can take place.
While the intensity of the ‘first-pass effect’ can vary from person to person, with some individuals even preferring their CBD concentration to be lower and more ‘slow-acting’ with longer results, the general consensus remains: the ‘first-pass effect’ happens to a lesser degree when the CBD is inhaled. Meaning that, when you vape, more CBD is absorbed with less waste and purportedly better effects.
In fact, vaping CBD has a high enough bioavailability of 50-60%, which is more than enough to significantly affect therapeutic change. This is because of a process known as diffusion- which is when a substance, such as vapourised CBD, is inhaled into the lungs and can absorb into the bloodstream with ease, due to a concentration gradient. Due to the fact that the concentration of CBD is significantly less, just outside of the lungs, the CBD can quickly diffuse into the blood with little hassle, as any gas will tend to move from a high to low concentration, or down the concentration gradient.
Because the lungs are so permeable, with a wide surface area, they’re more used to letting gaseous molecules in and out than worrying about metabolising anything. For one, when we inhale anything into our lungs, as long as it’s gaseous, more of that substance will enter the bloodstream in one go. Studies tell us that, when vaped, CBD’s possible effects on the system can be felt within 30-60 minutes. For another, CBD becomes more hydrophilic (water-soluble) when it is vapourised, allowing it to absorb into the bloodstream with ease- without you having to worry about the CBD lodging into the fatty tissues of the muscles, where it is less likely to be quickly ‘used’ by the body.
How Does CBD Help With Anxiety?
So, with us establishing that CBD’s possible therapeutic benefits can be felt at faster, more intense levels when vaped, let’s see how CBD may curb symptoms of anxiety.
There are a few ways to categorise anxiety. While anxiety disorders tend to branch out into different levels and types, we can label the main types of anxiety as such:
- Generalised anxiety disorder
- Social disorders
- Post-traumatic stress disorder (PTSD)
- Obsessive-compulsive disorder (OCD)
These four categories are umbrella terms for a broader range of issues surrounding anxiety. They can also vary in intensity and require different types of treatment, from medication to therapy. However, for the most part, anxiety is usually understood to stem from a response to feeling in some type of danger (which can be anything from physical to emotional, like an upcoming meeting with your boss). When a person begins to express anxiety over smaller triggers (like going outside or meeting with friends), this is usually diagnosed as an anxiety disorder.
So, how might CBD help your anxiety symptoms?
CBD and The Endocannabinoid System (ECS)
CBD has been known to indirectly affect the endocannabinoid system (ECS). This is a complex system which we all have, and is responsible for balancing processes in the body (also known as ‘homeostasis’, if you want to get scientific). In other words, the ECS keeps everything in good working order- from keeping our mood balanced, our appetite in moderation, and even ensuring that our cognitive processes (such as memory and perception) run smoothly. Even without outside help from CBD, our ECS can work on its own- by using our body’s natural endocannabinoids and ECS receptors.
Endocannabinoids, which are produced by the body, work by binding to ECS receptors, which are dotted around our whole body (particularly throughout our nervous system). Typically, ECS receptors are split into two types- CB1 and CB2; which control different processes. Where CB1 receptors tend to sit in the brain and along the central nervous system (CNS), CB2 receptors tend to line the gut and modulate the peripheral nervous system (PNS) alongside our immunity.
Cannabinoids, such as CBD, have the potential to stimulate the ECS into action. Where CBD isn’t thought to directly interact with CB1 and CB2 receptors, it may promote higher levels of certain endocannabinoids, which do work well with these receptors, and turn can help to modulate processes such as our anxiety responses (via the CNS). When endocannabinoids alone, can’t help to promote higher levels of feel-good neurotransmitters, such as serotonin, GABA, and even dopamine in our system, taking CBD has shown to raise these neurotransmitters without any chance of psychotropic effects.
CBD: Potentially Decreasing Anxiety
CBD promotes the release of two endocannabinoids, in particular: 2-AG and anandamide. So, unlike THC, it doesn’t ‘flood’ the CB1 and CB2 receptors or cause psychotropic effects. Instead, by impacting levels of already-existing endocannabinoids, CBD may increase the therapeutic benefits of our natural ECS. This is because both anandamide and 2-AG are known for their beneficial qualities- one major quality is significantly reducing the symptoms of anxiety in high enough doses (anandamide is even known as a ‘bliss’ compound in some circles!)
Studies have shown that higher levels of CBD can instantaneously help to modulate your fear response, typically associated with anxiety, which is a response to a trigger that a person imagines (even subconsciously) as a threat to their wellbeing or survival. In one 2019 study, researchers found that 300 mg to 600 mg a day was enough to significantly lower anxiety levels (in a group of 57 males).
It makes sense why a vape might be best, especially if you’re prone to high levels of anxiety which hit at inopportune moments. CBD e-liquids tend to vary in concentration- but you can be assured that very little of that concentration will be wasted in the metabolic process. With a vape, bioavailability is high enough that the CBD can absorb into the system fairly quickly, and change can occur.
Anandamide, also known as the ‘bliss molecule’, promotes an overall therapeutic response in the system. According to some studies, those who are ‘happier’ tend to have naturally higher levels of anandamide in their system. Typically, without the presence of CBD, anandamide is reabsorbed quickly by a protein called fatty acid amide hydrolase (FAAH). With CBD in the picture, FAAH’s activity is severely limited, meaning that anandamide can exist in the system for longer amounts of time.
High levels of anandamide can do all sorts of things for the body- from decreasing pain levels to reducing how much fear we perceive. Not only does anandamide bind to the CB1 receptors in the brain, which can promote higher levels of feel-good neurotransmitters (more on this later), but anandamide can also bind to TRPV1 receptors. When anandamide binds to these receptors, it tends to help lower our perception of pain and fear as well as increase wellbeing. A study conducted on rodents, shows us that, when FAAH is inhibited from reuptaking anandamide, it tends to bind to TRPV1, affecting a host of therapeutic benefits, from the regulation of body temperature to lowering our fear levels.
TRPV1 receptors tend to be located in the regions of the brain which control emotional and stress responses, which suggests why binding to them might help modulate things like pain and fear. These locations include the hippocampus, medial prefrontal cortex, and dorsolateral periaqueductal grey areas of the brain- and scientists hypothesise that TRPV1 might have such anxiolytic effects, because of where they’re situated in the brain.
Anandamide proves useful in many areas of our life- much like the happiness it creates- as we can clearly see the benefits of having the endocannabinoid in greater amounts within our system. Not only does anandamide help to lower anandamide levels by boosting our serotonin levels, but it can also activate homeostasis in the body by binding to CB1 and CB2 receptors all over the body.
One of the ways anandamide can be particularly useful for anxiety is down to new research, which tells us that higher levels of anandamide in the system have been linked to more nerve cells. The process, known as neurogenesis, essentially allows for better memory, learning, and cognition (clearer thoughts, basically). When it comes to helping your anxiety, anandamide’s potential to help promote neurogenesis in the body may prove valuable. Better cognition, perception, and memory could be one of the key ways to combat mental health disorders, such as depression and anxiety- since the two disorders often go hand in hand (they’re typically caused by the same chemical imbalances in the body) this makes sense.
Likewise, CBD levels have been shown to potentially promote the activity of the endocannabinoid 2-AG, which has a high affinity for CB1 receptors in the CNS. It is said to do this by inhibiting the enzyme, monoacylglycerol lipase, which tends to degrade 2-AG.
Studies have shown that higher levels of 2-AG in the system help to decrease inflammation, protect neurons, and increase feel-good neurotransmitter levels. More than a few studies have concluded that higher levels of 2-AG have helped reduce anxiety-like behaviours in animal models, reduce PTSD symptoms, and reduce the symptoms of depression.
While these studies didn’t categorically state that anxiety could be curbed by higher levels of 2-AG in the system, one did conclude that low levels of 2-AG (where the 2-AG pathway was disrupted in some way or another) meant the mice displayed higher levels of anxiety- suggesting that a relationship between 2-AG and anxiety does exist, though further testing is needed. The same study suggests that 2-AG activity in the amygdala region of the brain could play a key role in improving mood and reducing symptoms of anxiety and fear in the long term.
Higher levels of 2-AG have also been shown to curb stress; in particular, mice with higher levels of 2-AG in their amygdala were shown to be more resilient to stress.
As you might already know, higher levels of serotonin have been linked to lower cases of depression and anxiety disorders- as well as regulating our sleep schedule, appetite and even digestion. Serotonin predominantly resides in our brain, bowels, and blood platelets- playing a significant role in many of our central nervous system processes.
CBD and Serotonin
Luckily for us, CBD may, in fact, work with the serotonergic receptors in the brain, purportedly improving mood and lowering anxiety levels by a significant amount. Not only have studies posited that anandamide and 2-AG could play a role in helping to modulate serotonin levels in the brain, by activating CB1 receptors- it has also been confirmed that CBD may potentially have an influence on how the 5-HT pathway (through which serotonin travels) works.
5-HT receptors bind to serotonin (also known as the molecule, 5-HT), and this allows therapeutic change to affect the system. The 5-HT pathway can be a tricky one to modulate- since the overactivation of CB1 receptors in the brain has been shown to inhibit 5-HT receptors, preventing serotonin from doing its job. With anandamide and 2-AG in the system, there is a gentle activation of CB1 receptors in the brain, which allows the 5-HT pathway to regulate itself at an optimal level- promoting the secretion of serotonin in the body, without upsetting this precarious balance.
According to some studies, CBD may affect the way your system responds to already-existing levels of serotonin. This is because CBD may potentially bind to 5-HT receptors in the brain and stimulate therapeutic change before serotonin even enters the picture. Since the brain believes that the 5-HT receptors are activated, serotonin’s ‘feel-good’ pathway is in a great state of balance. This may affect positive change in the body- helping to lower anxiety levels, curb depression, and boost wellbeing.
According to other studies, anandamide and 2-AG’s potential to promote activity in TRPV1 receptors, as well as the 5-HT pathway, can potentially overstimulate the system. This suggests that your CBD dose needs to be moderate to high- but not overwhelming. Luckily, it’s rare for CBD to overwhelm the system since CBD itself doesn’t have a massive affinity for ECS receptors. There’s very little chance (as in, few instances have ever been recorded) for the system to become overloaded and start to skew perception, memory, and mood in the same way that a THC overdose (also known as a THC ‘high”) can do.
Before we begin, we do recommend that any beginner suffering from any chronic anxiety disorder refer to a medical professional before embarking on their CBD vape journey. While CBD supplements tend not to have as many side effects as standard medication, everyone’s body is unique and tends to react differently- even to the most natural of substances. Likewise, vaping isn’t always suitable for everyone- it can be potentially dangerous for people with weak lungs or asthma. It is important to consult and consider the advice of a medical professional before you choose to vape.
It’s hard to put a finger on what the correct dosage of CBD is for you. This is because, as so many studies out there have shown, there’s a great discrepancy when it comes to how much CBD it may take to impact your anxiety symptoms. Although the general consensus is 300mg-600mg, it can be hard to determine what’s right for you. There are several factors to consider when you’re dosing your CBD:
- Your metabolism
- Your body weight
- The concentration of CBD
- What type of anxiety disorder you have/ the severity of your disorder
A particularly important factor, and one that often gets missed in the dosing debate, is: what type of method are you using. With a CBD vape, as we’ve established, the bioavailability of CBD is pretty high- which means you’ll be getting a higher concentration of CBD, quickly and effectively, than if you took cannabidiol orally or sublingually.
Another thing to consider is what spectrum of e-liquid you want. As a rule of thumb, the more cannabinoids there are present, the more potent and effective your e-liquid will be.
‘Whole Plant’ CBD Vape Liquid
‘Whole plant’ e-liquid is the most potent type of vape juice out there- it essentially combines every single cannabinoid found in the hemp plant. This means that low, legal levels of THC are present in ‘whole plant’ liquid- which is nothing to worry about, because, according to UK law, the THC can’t exceed 0.2% concentration levels. That’s not enough to get you high, but it is enough to promote the ‘entourage effect’. This is when trace amounts of THC, alongside other cannabinoids which are typically found in the hemp plant, work together with CBD to make the product more effective.
‘Whole plant’ e-liquid typically contains natural waxes and lipids (found in the hemp plant, itself) which further promotes the ‘entourage effect’. Since any CBD product which can naturally mimic the ratio of cannabinoids and molecules found in the original hemp plant tends to be a lot more potent, a ‘whole plant’ e-liquid is considered highly potent and effective.
Combining the potency of ‘whole plant’ e-liquids with the high bioavailability of vaping, and ‘whole plant’ vape juice’s potency can be considered an excellent therapy against strong anxiety disorders, with many results anecdotally reported quickly and effectively.
Full Spectrum E-Liquid
Full-spectrum e-liquids also take advantage of the ‘entourage effect’, much like ‘whole plant’. However, unlike ‘whole plant’ e-liquids, full-spectrum doesn’t contain the lipids and wax found in the original hemp plant. This is because a full spectrum e-liquid won’t contain hemp paste.
Otherwise, full-spectrum e-liquids still contain legal levels of THC, with a mixture of cannabinoids- including terpenes, flavonoids, and phytocannabinoids to provide a rich CBD experience.
Broad Spectrum E-Liquid
Broad-spectrum e-liquids contain all the cannabinoids- except THC.
While broad-spectrum is still potent in its own right, drawing on the ‘entourage effect’, its lack of THC, even in trace amounts, means the e-liquid is less potent than ‘whole plant’ or full spectrum.
Since THC is the most abundant cannabinoid in the cannabis Sativa plant, a broad spectrum e-liquid can’t quite capture the same ratio of the original hemp plant- meaning that the potency of the other cannabinoids is reduced (though not by much).
Nonetheless, broad-spectrum is perfect for those who want to avoid THC’s psychoactive properties altogether.
VAAY’s Selection of CBD Vape Pens
At VAAY, we believe that no CBD product is quite as effective, is it is without the ‘entourage effect’. Which is why we have a selection of vape diffuser pens with added terpenes- from mint and citrus (to uplift and elevate your mood) to pinene (to help you relax). A wealth of research can tell you that terpenes are extremely valuable for the system- not just to promote the strength of CBD, but for additional possible benefits.
Our lemon-infused pen contains limonene, among other terpenes, to potentially prevent oxidative stress, lift the mood, protect against gastrointestinal diseases, promote antimicrobial benefits, and more.
Our mint-infused pen has additional terpenes, such as beta-caryophyllene and linalool, to purportedly stimulate wellbeing and help modulate GABA receptors in the brain- essential for lowering anxiety and promoting wellness. Menthol’s potential to inhibit the growth of cancer cells and reduce pain and inflammation also gives it a therapeutic reputation.
Our herbal pen has pinene, limonene, and linalool to help prevent oxidative stress, decrease anxiety and stress, and improve cognition.
And lastly, our fruit-infused pen has a cocktail of terpenes, including geraniol, which has properties as a neuroprotective agent, as well as helping to ease inflammation, protect the heart, and promote better cognition.
Whether you suffer from anxiety or simply want to try CBD to promote your own wellbeing, the beauty of cannabidiol lies in its versatility. One of the most efficient methods for taking CBD is by vaping it- which allows the body to absorb CBD at quicker, more effective rates. This can be perfect for those of us who might need a quick way to combat rising symptoms of anxiety.
So, if you’re the type of person that values portability, comfort, ease, and effectiveness, why not pick up a CBD vape pen from VAAY, and see what all the fuss is about?